Yildirim Cinar, A great. Mete Senyol, Kamber Duman, Bloodstream viscosity and you will blood pressure level: character out-of temperatures and you will hyperglycemia, Western Record regarding Blood pressure levels, Frequency fourteen, Matter 5, , Users 433–438,

Abstract

We planned a study to research the relations among blood pressure (BP), viscosity, and temperature in healthy subjects and among BP, viscosity, and glucose in diabetics. With simple random sampling method, 53 healthy and 29 diabetes mellitus (DM) type II subjects were selected. Parameters were determined with capillary viscometer and glucometer at 22°C, 36.5°C, and 39.5°C in healthy subjects, and at 22°C on diabetic patients during OGTT with 75 g of glucose. Statistical evaluations of the data were made with regression analysis, Student t test, Spearman’s correlation, and analysis of variance. When temperature decreased from 36.5°C to 22°C, blood viscosity increased %. This increase resulted in a % decrease in blood flow rate. According to the Hagen-Poiseuille equation, the required BP increase for compensation of the resulting tissue ischemia was %. Also, a % decrease in erythrocyte deformability and % increase in plasma viscosity were seen. When temperature increased from 36.5° to 39.5°C, blood viscosity decreased %. This caused % decrease in blood flow rate, and % decrease in BP, according to the equation. Erythrocyte deformability increase of 9.92% and plasma viscosity decrease of 4.99% arose from the temperature rise. There is a correlation between total data for temperatures and viscosities (r = ?0.84, P < .001). When the mean value of blood glucose increased from 100 to 400 mg/dL, viscosity increased 25% (r = 0.59, P = .002). In this state, blood flow rate decrease was 20% and BP increase for physiological compensation was 25%. Consequently, temperature, glucose and viscosity levels of blood are important factors for BP. Am J Hypertens 2001;–438 © 2001 American Journal of Hypertension, Ltd.

The purpose of all of our study is always to check out the relationship one of temperature, glucose attention, and you can viscosity out of blood and plasma, in order to estimate its consequences towards the blood pressure (BP) predicated on Hagen-Poiseuille’s hydrodynamics formula.

If the human circulatory system is considered as a closed system, hemodynamic equilibrium can be determined according to Poiseuille’s equation through the pressure, viscosity, flow rate, velocity of blood, and vessel diameter. Viscosity can be defined as the resistance of fluids against flow. The resistance hookup websites like craigslist for blood circulation includes friction between the blood elements and between the vessel lumen and blood. To make a fluid flow, the application of energy is required. Therefore, the energy of the circulatory system is spent in correlation with the viscosity level of blood. Energy forms of the circulatory system are BP and blood flow velocity. The velocity (v) and pressure of blood flow can be determined with Poiseuille’s equation as v = 1/4?L (F₁ ? F₂) (a 2 ? r 2 ), and also BP rate (Q) can be expressed from the above equation as Q = ?a 4 /8 ?L (F₁ ? F₂), where ? is the viscosity of the fluid, F₁ and F₂ are the initial and the final cross sectional pressures of blood, L is the length, a is the radius of vessel, and r is the distance from the center of the vessel for a flowing particle. 1, 2 Thus, to keep the equilibrium of the equation constant in the circulatory system, BP will increase when viscosity increases.

Bloodstream viscosity and blood pressure levels: character out of temperature and you will hyperglycemia

It’s been revealed one to between % and you can % values regarding hematocrit, all the 11% rise in hematocrit expands blood viscosity because of the 20%. In this state, according to Poiseuille’s equation, flow speed minimizes by %, which may result in muscle ischemia. To save the newest circulatory system in equilibrium (which is, keeping the fresh circulate price adequate and you can preventing tissues ischemia), a great 20% escalation in BP or cuatro.66% vasodilation becomes necessary. 3 But not, the human being circulatory method is not an accurate closed system, just like the blood viscosity are going to be altered towards assimilation out-of dinner otherwise pills. 4–8 At the same time, the consequences regarding fat and of certain medicines with the blood viscosity and you may hemodynamics including BP have been claimed. Since the atherosclerotic ships do not dilate good enough because a reaction to vasodilator medication, it’s been advised one increased blood viscosity can only getting paid that have good BP escalation in for example points. 9–several And, new relationships one of BP, headache, coagulation, blood circulation acceleration, and you may bloodstream viscosity was indeed explained via the beliefs out of hemodynamics. 13, 14